Ascend Tysabri Trial for SPMS

[0485c10]

Updated my home page(Tysabri page 2 1/26/2012) to include links to 2 articles announcing the start of phase 3b study of tysabri use in SPMS. one article by pharmiweb and one article by NASDAQ.

i suspect there are many using tysabri that are SP, already, just still diagnosed RR for insurance flexibility.

[socrmom]

Have SPPMS went to drs yesterday and asked if I was willing to take Tysabri a study was starting. Just catching up on all articles from everyone currently taking Tysabri. Right now I'm scared. I have a pump so an MRI is awkward and I'm sorry for doing that. If I decide to take Tysabri, will post.

[GardeningMSer]

Tysabri seems to be working for me.

I'm dx'd with RR, though I believe I'm either PPMS or SPMS, my first symptoms occurred 12 years ago.

About 7 years ago I started using a cane, within two years when my office was moved I got a scooter for use outside my home, and a few years later got an electric wheel chair for indoors.

My cognitive issues are very minor, best as I can tell due as much to my age (63) as MS.

I've taken C, R, and Novantrone before switching to T about four and half years ago. I'm also taking Ampyra.

I have anti-bodies to the PML virus, this will not get me off T.

I am fairly certain that T has delayed progression - I'm still able to walk and enjoy life greatly.

During the past year I moved and left my wheelchair in my large old house, not needing it in my new apartment. During the last six months I had PT - physical therapy - and a Walkaide. I also exercise an hour or two a week on indoor bicycle.

I no longer have spasticity in my thighs during the day - it used to be very painful, and don't need Tizanadine at dinner time, taking it bed time only because I'm in the habit and it makes me drowsy. I rarely take pain killers with the exception of Celebrex due to a slightly arthritic hip. I used to be a very regular Tylenol user.

I consider myself very, very fortunate and think Tysabri is really helping.

[KyleW]

I'm not sure what it says on my paperwork, but my doc dx'd me as SPMS. That was in October. I've had 3 Tysabri infusions and no insurance hiccups.

[lindaincolorado]

I am probably spms-dx 1988. Tysabri has been great for me