I don't know about the chemo. I didn't readanything about 'ablation'. All that I know is that they chose their trial participants from their own patient list.
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Kristy Cruise on 60 minutes
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How do they (Tisch) determine whether treatment has worked on PPMS/SPMS when their criteria requires pretty stable disease? I mean, I know that they require an MRI 27 months after the last treatment but I know there are people who don't progress very quickly or plateau for a period of time.
- Significant disability shown by an Expanded Disability Status Score (EDSS) of 3.0 or greater that was not acquired within the last 12 months
- Stable disease state as evidenced by a lack of gadolinium-enhancing lesions on an MRI and by a stable MRI disease burden (number of T2 lesions and size of lesions) in the last six months and no significant change in EDSS (1 point or more) in the last 12 months
http://clinicaltrials.gov/ct2/show/NCT01933802
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