Microparticles that activate regulatory T-cells, or Tregs, an immune cell type with anti-inflammatory properties, reversed the accumulation of physical disability due to multiple sclerosis (MS) in a mouse model of the neurodegenerative disorder, a new study shows.
Use of the novel strategy even cured some of the animals.
“We developed a method for ‘tipping the balance’ of the T cells reaching the central nervous system from effectors to regulatory T cells, or T regs, that modulate the immune system and have been shown to prevent autoimmune reactions,” Giorgio Raimondi, PhD, a professor at Johns Hopkins University School of Medicine and co-author of the study, said in a press release.
The study’s researchers called it “a promising platform for treatment of autoimmune diseases” like MS.
Complete article:
https://multiplesclerosisnewstoday.c...s-mouse-model/
Use of the novel strategy even cured some of the animals.
“We developed a method for ‘tipping the balance’ of the T cells reaching the central nervous system from effectors to regulatory T cells, or T regs, that modulate the immune system and have been shown to prevent autoimmune reactions,” Giorgio Raimondi, PhD, a professor at Johns Hopkins University School of Medicine and co-author of the study, said in a press release.
The study’s researchers called it “a promising platform for treatment of autoimmune diseases” like MS.
Complete article:
https://multiplesclerosisnewstoday.c...s-mouse-model/
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