The volume of brain lesions in people with multiple sclerosis (MS) does not indicate the degree of severity or disability, according to a study completed at the University of Buffalo and presented at the annual meeting of the Americas Committee for Treatment and Research in Multiple Sclerosis.
Brain lesions are areas of damage caused by injury or illness.
These are markers medical professionals use to determine MS progression and modify treatments to slow the accumulation of lesions.
However, the new study suggests that the volume of lesions in the brain’s white matter does not provide information on the degree of disability.
The findings have not been published yet in a peer-reviewed journal.
For the study, researchers compared two sets of people with MS between the ages of 30 and 80.
They matched each participant with a “twin” who was the same gender and had similar durations of MS. However, they differed in physical and cognitive disabilities.
The scientists said they did not find material differences in white matter brain lesions. However, participants with a severe disability did have gray matter loss even though the whole brain volume was comparable in both groups.
The researchers reported that the more severely affected group also had:
- Pronounced atrophy of the connection between the brain and the spinal cord.
- A more advanced loss of neurons.
Complete article:
https://www.healthline.com/health-ne...ilities
Brain lesions are areas of damage caused by injury or illness.
These are markers medical professionals use to determine MS progression and modify treatments to slow the accumulation of lesions.
However, the new study suggests that the volume of lesions in the brain’s white matter does not provide information on the degree of disability.
The findings have not been published yet in a peer-reviewed journal.
For the study, researchers compared two sets of people with MS between the ages of 30 and 80.
They matched each participant with a “twin” who was the same gender and had similar durations of MS. However, they differed in physical and cognitive disabilities.
The scientists said they did not find material differences in white matter brain lesions. However, participants with a severe disability did have gray matter loss even though the whole brain volume was comparable in both groups.
The researchers reported that the more severely affected group also had:
- Pronounced atrophy of the connection between the brain and the spinal cord.
- A more advanced loss of neurons.
Complete article:
https://www.healthline.com/health-ne...ilities
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