Two days ago, my bf finished a 3 day IVSM for a mid relapse. This was his 2nd infusion - the first one was 6 weeks ago when he was first diagnosed. During the first round he was very energetic and hyper. This time it is the complete opposite. It seemed as soon as he ended is first day he became tired. This tiredness only seems to be getting worse. Today, even after about 14 hours of sleep, he his struggling to keep his eyes open or get out of bed. I was wondering if anyone else has experienced this side effect from IVSM?