Thank to Temagami for this link. I haven't gotten to the original article yet but this synopsis was interesting and seems to indicate the results from a meta analysis downplayed the efficacy of medications, even the newer meds, in older people with MS, on average.
My MS specialist actually said something about considering no meds at my last appointment due to being "stable" for so long and I thought he lost his mind, especially for the next 8 or so years while I'd like to continue working if I'm able.
Have you heard this before? Any insights/opinions?
"Specifically, the model predicted that on average DMTs cease to be effective beyond the age of approximately 53 years. When the low- and high-efficacy DMTs were modelled separately, the high-efficacy drugs were more effective than low-efficacy drugs only when used in people of 40.5 years or younger; after this point there was no benefit in the average person with MS using high-efficacy drugs. The authors highlighted that the continuous loss of efficacy with age reported in this study supports the notion that “progressive MS is simply a later stage of the MS disease process”."
From:
https://www.msbrainhealth.org/treatm...-linked-to-age
My MS specialist actually said something about considering no meds at my last appointment due to being "stable" for so long and I thought he lost his mind, especially for the next 8 or so years while I'd like to continue working if I'm able.
Have you heard this before? Any insights/opinions?
"Specifically, the model predicted that on average DMTs cease to be effective beyond the age of approximately 53 years. When the low- and high-efficacy DMTs were modelled separately, the high-efficacy drugs were more effective than low-efficacy drugs only when used in people of 40.5 years or younger; after this point there was no benefit in the average person with MS using high-efficacy drugs. The authors highlighted that the continuous loss of efficacy with age reported in this study supports the notion that “progressive MS is simply a later stage of the MS disease process”."
From:
https://www.msbrainhealth.org/treatm...-linked-to-age
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