Factors for ms prognosis?

[Medina89]

What does the new study say?
Over the course of the study, 1,821 people (35 percent) developed secondary
progressive MS (SPMS). People progressed to this later stage at very
different rates. Those with the fastest progression developed SPMS less than
12 years after their initial MS diagnosis, while those with the slowest
progression took more than 32 years.
Men were more likely than women to progress quickly. This wasn't entirely
surprising, as other studies have suggested that the female hormone
oestrogen may help protect against nerve damage. The researchers also
found a higher chance of early progression among people who had movement
problems (motor symptoms) when they were first diagnosed with MS.
However, they didn't find any link with other types of early symptoms, such as
vision problems or numbness.
People diagnosed with MS at a younger age generally had a slower
progression, which confirms previous findings. But the researchers point out
that this doesn't necessarily translate into a better long-term outlook. Although
people diagnosed at a younger age may take longer to convert to SPMS, they
are still typically younger at the onset of Spms

[Seasha]

I found this study you're talking about - http://jnnp.bmj.com/content/suppl/20...tember2010.pdf

Further down it states:

How reliable are the findings?
This was a large and well-conducted study. The researchers gathered their
information from a robust database of health records, covering more than 80
per cent of people with MS in British Columbia, Canada. In their analysis, they
looked only at people who weren't taking medicines that can slow the
progression of MS, called immunomodulatory drugs (IMDs). This makes it
more likely that their results reflect genuine trends in the natural course of MS.
However, this type of study can't tell us why certain factors may be associated
with a faster onset of secondary progressive MS. Instead, these findings are
valuable primarily to help guide future research tobetter understand this
disease and how to treat it.

There is some evidence to help support that treating with a DMT early in your treatment journey might reduce physical disability progression. Remember, your healthcare team is always your best resource for questions related to MS and your treatment.

https://www.abovems.com/en_us/home/t...ing-early.html

And as stated, a healthy diet, getting enough sleep, minimizing stress and keeping your mind active also plays an important role.

[Ant1981]

Prognosis factor

Recovery from a exacerbation also is listed as a better outcome for prognosis I was told by my neuro.

[pennstater]

To my knowledge, I don't think any studies have been done on the oral and infused DMTs and how taking them impacts SPMS timeline.

Part of it may be the duration of time the meds have been available and as a first line defense. I am sure that the studies get harder when you try to find subjects only on one medication. But I would expect some studies in the next five years or so.

Ant1981 - recovery from relapse has been an indicator for a favorable prognosis. I have read the same thing your neuro told you.