A very interesting read about how DNA may play a role in the risk of developing MS, but also how the disease course may play out. We often say, "everyone's MS is different," but science eventually be able to match you with a few others based on your genes!
With over 110 MS risk genes identified to date, a new genetic study published in the Multiple Sclerosis Journal in December 2014 has shown that having more than one MS risk gene may be associated with an earlier age at onset of relapsing MS symptoms. For example: In a group of over 900 people with relapsing-remitting MS, researchers from the San Raffaele Scientific Institute in Italy found that those people who had a greater number of MS risk gene variants, also tended to show an earlier age of symptom onset. The team also found preliminary evidence that these genes may have the opposite effect in a group of over 500 people with MS that was progressive from outset, instead showing association with a later age of progressive illness onset.
The complete story can be found here: http://www.msra.org.au/ms-risk-genes...e-and-severity
With over 110 MS risk genes identified to date, a new genetic study published in the Multiple Sclerosis Journal in December 2014 has shown that having more than one MS risk gene may be associated with an earlier age at onset of relapsing MS symptoms. For example: In a group of over 900 people with relapsing-remitting MS, researchers from the San Raffaele Scientific Institute in Italy found that those people who had a greater number of MS risk gene variants, also tended to show an earlier age of symptom onset. The team also found preliminary evidence that these genes may have the opposite effect in a group of over 500 people with MS that was progressive from outset, instead showing association with a later age of progressive illness onset.
The complete story can be found here: http://www.msra.org.au/ms-risk-genes...e-and-severity
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