Campath (Alemtuzumab) news

[ToddwithMS]

I just saw this abstract in The Lancet:
"Alemtuzumab reduced disease activity compared with interferon beta-1a in most of the analysed subgroups. Significantly greater numbers of patients experienced sustained improvement in disability after treatment with alemtuzumab than interferon beta-1a. The efficacy offered by alemtuzumab is a substantial advance in the treatment of multiple sclerosis."

http://www.thelancet.com/journals/la...020-5/abstract

Wow! I'll have to ask my neuro about this stuff. But no idea how it compares to Ty...

Todd

[0485c10]

Alemtuzumab will be sold as Campath for Leukemia &
Lemtrada for MS. Lemtrada will be more expensive than Campath because of what each market will tolerate. the ms market will tolerate higher prices.

i already let my neuro know i was interested in this drug when it gets fda approval projected for late next year.

the once a year dosing is what i find most attractive, but i believe there is greater risk when using Lemtrada than with Tysabri? Tysabri has a low risk of a very dangerous disease & Lemtrada has a greater risk of a serious but treatable disease, but the risk is greater. we will know when they release the trial data, until then i'm just speculating..


http://www.bloomberg.com/news/2011-0...s-success.html


your article doesn't mention cancer--it says thyroid disorders and immune thrombocyopenic--which i just google it its the trendancy to bleed(leukemia?). death can be from Hemorrhage..requires long term use of cortisteroid or an immunosuppressive meds---so i might end up trading up to a yearly ms treatment requiring immunosuppressant and steroids looks like there may be no dosing benefit to lemtrada..darn! i think its benificial for the person that has failed on ty & that's not me & now that i know that immunosuppressants and steroids are need to use it, i'm not so enthusistic. thanks for posting this.

immune thrombocyopenic
http://emedicine.medscape.com/article/202158-overview

[0485c10]

more links on it....

http://www.mult-sclerosis.org/Campath1H.html

http://www.bloomberg.com/news/2011-0...s-success.html

[CrazyCatLady]

I just think it is exciting and Wonderful that more drugs are on their way!!! Steps closer to a cure!!!