Mastinab is an oral medication, and it is not a typical immunosupressant, which sounds good to me.
From the article:
~ “These results are the start of a possible revolution in the treatment of multiple sclerosis, as it is the first time a treatment has shown efficacy in both progressive forms of this [disease],” Patrick Vermersch, MD, PhD, the trial’s main coordinator, said in a press release.
~ Masitinib (formerly known as AB1010) is an oral, selective tyrosine kinase inhibitor that works by blocking the activity of mast cells, microglia, and macrophages — immune cells people are born with that are believed to play important roles in progressive MS. By suppressing these cells, the therapy is expected to limit neurodegeneration in progressive forms of the disease.
~ In conclusion, the trial’s results showed that the low dose of masitinib had a sustained and significant benefit in disability progression in a broad population of progressive MS patients over two years, suggesting that the therapy “may provide a new treatment option for PPMS and non-active SPMS,” Vermersch said.
The researcher also noted that masitinib’s safety profile “is suitable for long-term administration.”
In AB Science’s release, Vermersch noted: “Masitinib can be administered on a long-term basis as it is not an immunosuppressive treatment, which is particularly important in patients who are to receive long-term treatment and who, for some, have already an immune system weakened by previous treatments or because of their age.”
https://multiplesclerosisnewstoday.c...02-study-show/
From the article:
~ “These results are the start of a possible revolution in the treatment of multiple sclerosis, as it is the first time a treatment has shown efficacy in both progressive forms of this [disease],” Patrick Vermersch, MD, PhD, the trial’s main coordinator, said in a press release.
~ Masitinib (formerly known as AB1010) is an oral, selective tyrosine kinase inhibitor that works by blocking the activity of mast cells, microglia, and macrophages — immune cells people are born with that are believed to play important roles in progressive MS. By suppressing these cells, the therapy is expected to limit neurodegeneration in progressive forms of the disease.
~ In conclusion, the trial’s results showed that the low dose of masitinib had a sustained and significant benefit in disability progression in a broad population of progressive MS patients over two years, suggesting that the therapy “may provide a new treatment option for PPMS and non-active SPMS,” Vermersch said.
The researcher also noted that masitinib’s safety profile “is suitable for long-term administration.”
In AB Science’s release, Vermersch noted: “Masitinib can be administered on a long-term basis as it is not an immunosuppressive treatment, which is particularly important in patients who are to receive long-term treatment and who, for some, have already an immune system weakened by previous treatments or because of their age.”
https://multiplesclerosisnewstoday.c...02-study-show/
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