In January 2013 I began having burning sensation nerve pain on the top and inside of my thighs. Tight pants or cold wind would make the burning worse and especially at night. I have also had muscle twitching all over but mainly in my feet, legs, and arms. Brain fog will come and go.

I had clean MRIs, clean EMGs, but 3 positive ANA tests that were as high as 1:640. Although the ANA test was positive the tests for specific Autoimmune diseases have been negative. My vitamin D level was low but is back to normal and symptoms still persist.

I’ve lived with the nerve pain predominantly in my legs for the past 7 years, some days worse than others.

Fast forward to 2020, and I have more trouble concentrating, feels like I’m seeing but not processing fast enough/concentrating and some cases of sensory overload. Diagnosed with PLMD, and more nerve pain in the same spot in my thighs, arms, shoulder and back. Haven’t been able to get any answers.

I had MRI of my brain and C-spine 1.5T which was clear last week. EMG/NCV was also clear. Still worried that I could have MS as my thighs continue to burn and feel like my visual processing is slow. Hopeful that 2 clean MRIs, 1 in 2013 and 1 in 2020 make it unlikely..

Also, my neuro said my knee reflexes were "brisk" but not pathological/abnormal.

Anyone else have these symptoms or feel that they are indicative of MS? Haven't been able to get any answers and frustrated after 7 years.