I developed inflammatory arthritis in my right foot 4 days after my Tysabri infusion. All my providers are very confused. They are starting me on Plaquenil for the inflammation. I'm not seeing a lot on the internet about this sort of reaction to Tysabri. All my blood work is negative for RA, gout, etc. Has anyone else heard of anything like this?
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Here is a case of rheumatoid arthritis being linked to Tysabri:
https://www.sciencedirect.com/scienc...11034820300122
Have you seen a rheumatologist?
Patients with inflammatory arthritis should be promptly referred to a rheumatology for further evaluation.
Negative bloodwork does not exclude rheumatoid arthritis. Patients who lack both RF and anti-CCP antibodies may be diagnosed with RA based upon findings otherwise characteristic of RA.
I hope Plaquenil helps and your inflammatory arthritis resolves soon, with no further issues.
Best wishes and please keep us updated.Kimba
“When you change the way you look at things, the things you look at change.” ― Max Planck
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Originally posted by KatW View PostI developed inflammatory arthritis in my right foot 4 days after my Tysabri infusion. All my providers are very confused. They are starting me on Plaquenil for the inflammation. I'm not seeing a lot on the internet about this sort of reaction to Tysabri. All my blood work is negative for RA, gout, etc. Has anyone else heard of anything like this?
I do have arthritis in knees and hip, but not Tysabri related. Both started before and just age related. Come by it naturally - both parents had it.
What are they recommending you do? Will you stay on Tysabri?
Hope the inflammation resolves for you.Kathy
DX 01/06, currently on Tysabri
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Thank you both for the replies. The rheumy thought it was RA but everything was completely normal even my inflammation labs. She is excluding RA because it is only on one side. The Tysabri is on hold for now until we figure out what is going on. I'm taking myself to a dermatologist to rule out psoriasis. I thought osteoarthritis too but she sees inflammation in the joints. We are just doing Plaquenil for now since it will not react with the Tysabri.
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I have had Arthritis
Since I started Tysabri in 2013, I have had “flares” of Arthritis. I was tested for RA as well....it was all negative to include bloodwork, xrays and CT. It is in my hands and arms and I go through true flares. Could be aging....I am now 56, but my docs do feel it could be related to the TY. But it certainly not bad enough to come off the drug yet. 🌹🌹🌹Katie
"Yep, I have MS, and it does have Me!"
"My MS is a Journey for One."
Dx: 1999 DMDS: Avonex, Copaxone, Rebif, currently on Tysabri
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Linda, and others.
Originally posted by lindaincolorado View PostHi Kathy,
A few days ago I started having pain (on and off) in my left hip. Arthritis ?? I will see my PCP in a few weeks - regular appt. A friend said "hip replacement" Your post sounds like it is something you just live with..true?
Thanks
Linda
MaryGod Bless and have a good day, Mary
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