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    Mabhtera/Rituximab

    Anyone on this dmt ? My neurologist suggested it and on net its mostly positive but i am afraid of pml,what are the odds? My dr says no cases in ms but still i am very worried

    #2
    Originally posted by Medina89 View Post
    Anyone on this dmt ? My neurologist suggested it and on net its mostly positive but i am afraid of pml,what are the odds? My dr says no cases in ms but still i am very worried
    I have been on Rituximab going on 2 years and doing well. It's an anti-cd20 that is quite similar to ocrelizumab (Ocervus) in action. Since there have been no reported cases of PML for MS patients on rituximab your chances are probably considered nil.

    I wish you well...

    Comment


      #3
      Originally posted by Marco View Post
      I have been on Rituximab going on 2 years and doing well. It's an anti-cd20 that is quite similar to ocrelizumab (Ocervus) in action. Since there have been no reported cases of PML for MS patients on rituximab your chances are probably considered nil.

      I wish you well...
      Thank you

      But there have been cases of pml with other diseases i read?

      Comment


        #4
        Originally posted by Medina89 View Post
        Thank you

        But there have been cases of pml with other diseases i read?
        I'm glad you are being proactive about your medication choices.

        People with other diseases get a lot more rituximab than we do putting them at greater risk.

        Only you can decide what risk(s) make sense to you. I am jcv+ and get a quarterly CBC to monitor my blood counts. That doesn't rule out all risks, but for me the benefits outweigh the risks.

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          #5
          What dose do you get? i think my neuro said 500 mg will be enough ,but i do not remember that detail

          Comment


            #6
            Originally posted by Medina89 View Post
            What dose do you get? i think my neuro said 500 mg will be enough ,but i do not remember that detail
            I will answer your question, but please do not use my experience to form your decision. As individuals, we all respond differently to medications and have unique circumstances.

            Starting out
            Day 1 - 500 ml
            Day 14 - 500 ml

            Followed by
            500 ml every 6 months

            I wish you well...

            Comment


              #7
              Originally posted by Marco View Post
              I will answer your question, but please do not use my experience to form your decision. As individuals, we all respond differently to medications and have unique circumstances.

              Starting out
              Day 1 - 500 ml
              Day 14 - 500 ml

              Followed by
              500 ml every 6 months

              I wish you well...
              Thank you!

              Comment

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