Mice treated with medrysone saw increases in oligodendrocyte activity, myelin basic protein levels.
Treatment with medrysone, a glucocorticoid approved in the U.S. as a topical treatment for certain inflammatory eye diseases, improved repair of myelin in a mouse model of demyelination, a new study shows.
The results suggest medrysone may be a useful treatment for multiple sclerosis (MS), which is caused by inflammation that damages the myelin sheath in the brain and spinal cord. The study, “Myelin repair is fostered by the corticosteroid medrysone specifically acting on astroglial subpopulations,” was published in eBioMedicine.
Complete study: https://multiplesclerosisnewstoday.com/news-posts/2022/08/31/medrysone-may-be-useful-ms-treatment-prompts-myelin-repair/
Treatment with medrysone, a glucocorticoid approved in the U.S. as a topical treatment for certain inflammatory eye diseases, improved repair of myelin in a mouse model of demyelination, a new study shows.
The results suggest medrysone may be a useful treatment for multiple sclerosis (MS), which is caused by inflammation that damages the myelin sheath in the brain and spinal cord. The study, “Myelin repair is fostered by the corticosteroid medrysone specifically acting on astroglial subpopulations,” was published in eBioMedicine.
Complete study: https://multiplesclerosisnewstoday.com/news-posts/2022/08/31/medrysone-may-be-useful-ms-treatment-prompts-myelin-repair/