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    Bafiertam

    UPDATE: FDA-Approved Oral Bafiertam™ (Monomethyl Fumarate) Now Available for Prescription

    September 1, 2020

    (Originally released in May 3, 2020; Updated with additional details)
    The U.S. Food and Drug Administration approved Bafiertam™ (monomethyl fumarate, Banner Life Sciences) in late April 2020 as an oral disease-modifying therapy for adults with relapsing forms of MS. Bafiertam (pronounced bah”feer’tam) is similar to Tecfidera® and Vumerity® but has a distinct chemical structure. This therapy is now available for prescription.

    >Relapsing forms of MS includes people with clinically isolated syndrome (an initial episode of neurological symptoms), relapsing-remitting MS, and active secondary progressive MS. People with active secondary progressive MS have had progression of disability but still experience acute relapses or new MRI activity.

    >Although their exact mechanisms of action are not known, fumarate therapies are thought to modulate the immune response underlying MS to be less inflammatory, and may have antioxidant properties that could be protective against damage to the brain and spinal cord.

    >Because of its similarity to Tecfidera, Bafiertam’s approval was based largely on the FDA’s findings of safety and efficacy for Tecfidera and “bioavailability” studies in healthy subjects comparing dimethyl fumarate to Bafiertam. Twice-daily Tecfidera was shown in clinical trials to significantly reduce relapses and disease activity on MRIs, and in one trial it reduced progression of disability.

    >People prescribed Bafiertam will take a lower dose for one week, and then a maintenance dose of two capsules taken by mouth twice a day.

    >The price of Bafiertam has been announced as $69,480 per year. The actual cost to individuals will depend on the provisions of their insurance coverage and the degree to which they will be eligible for programs designed to assist with out-of-pocket costs.

    More info:

    https://www.nationalmssociety.org/Ab...ethyl-Fumarate)

    Kimba

    “When you change the way you look at things, the things you look at change.” ― Max Planck

    #2
    Thanks for this information, Kimba! It seems like the link you provided is a "file not found".

    Here it is- https://www.nationalmssociety.org/Ab...ethyl-Fumarate)
    1st sx '89 Dx '99 w/RRMS - SP since 2010
    Administrator Message Boards/Moderator

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      #3
      Originally posted by Seasha View Post
      Thanks for this information, Kimba! It seems like the link you provided is a "file not found".

      Here it is- https://www.nationalmssociety.org/Ab...ethyl-Fumarate)
      Try this one:

      https://www.nationalmssociety.org/Ab...thyl-Fumarate)

      PPMS for 22 years (dx 1998)
      ~ Worrying will not take away tomorrow's troubles ~ But it will take away today's peace. ~

      Comment


        #4
        Thanks KoKo! Don't know why mine didn't work, but 3rd try is the charm!
        1st sx '89 Dx '99 w/RRMS - SP since 2010
        Administrator Message Boards/Moderator

        Comment


          #5
          Originally posted by Seasha View Post
          Thanks KoKo! Don't know why mine didn't work, but 3rd try is the charm!
          Seasha, if you click 'quote', under your post #2, and look at the url, you will see that there is a parenthesis between the ending url and the quote tag. The parenthesis should be after the word Fumarate. That's enough to mess up the link.
          PPMS for 22 years (dx 1998)
          ~ Worrying will not take away tomorrow's troubles ~ But it will take away today's peace. ~

          Comment


            #6
            Originally posted by KoKo View Post

            Seasha, if you click 'quote', under your post #2, and look at the url, you will see that there is a parenthesis between the ending url and the quote tag. The parenthesis should be after the word Fumarate. That's enough to mess up the link.
            That is so wierd. I wonder why it cut off the parenthesis like that on both our links?

            Thanks for figuring out the fix, KoKo!
            Kimba

            “When you change the way you look at things, the things you look at change.” ― Max Planck

            Comment


              #7
              Originally posted by Kimba22 View Post

              That is so wierd. I wonder why it cut off the parenthesis like that on both our links?

              Thanks for figuring out the fix, KoKo!
              Hi Kimba

              It's a mystery, for sure, how that happened.

              I have found that even an extra space in the link, or any added or missing character, can mess up a link.

              The most common seems to be a missing closing bracket on the url tag ( [/url ), which is easy to do during a copy and paste.

              But how that parenthesis got misplaced, well that is baffling!

              PPMS for 22 years (dx 1998)
              ~ Worrying will not take away tomorrow's troubles ~ But it will take away today's peace. ~

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