FDA approved Disease Modifying Therapies
  • Avonex (interferon beta-1a) - a once-a-week self-injection
  • Aubagio (teriflunomide) - a once-a-day oral tablet
  • Betaseron/Extavia (interferon beta 1b) - an every-other-day self-injection
  • Copaxone 20 / Copaxone 40 (glatiramer acetate) - Copaxone 20 is self-injected daily. Copaxone 40 is self-injected 3x per week.
  • Gilenya (fingolimod)- a once-a-day oral tablet
  • Glatopa (generic equivalent for Copaxone, produced by Sandoz) - 20 mg self-injected daily/ 40 mg self-injected 3x per week
  • Glatiramer Acetate Injection (generic equivalent for Copaxone, produced by Mylan) - 20 mg self- injected daily/ 40 mg self-injected 3x per week
  • Lemtrada (alemtuzumab) - IV infusion given over the course of 5 consecutive days, followed 1 year later with a 3 day consecutive course.
  • Mavenclad (cladribine) - Oral medication administered orally and divided into 2 yearly treatment courses (1.75 mg per kg per treatment course). Each treatment course is divided into 2 treatment cycles.
  • Mayzent (siponimod) - After treatment titration (5 days) the recommended maintenance dosage is 2 mg taken orally once daily starting on Day 6
  • Novantrone (Mitoxantrone) - IV infusion given once every 3 months, limited to a maximum of two to three years.
  • Ocrevus (ocrelizumab) - IV infusion. 1st dose divided by 2 doses, then given once every 6 months
  • Plegridy (peginterferon beta-1a) - a once-every-14-day self-injectible med
  • Rebif (interferon beta-1a) - a 3-times-per-week self-injection
  • Tecfidera (dimethyl fumarate) - a twice-per-day oral capsule
  • Tysabri (natalizumab) - IV infusion given once every 4 weeks
Vumerity (diroximel fumarate) Oral medication taken twice daily.

More information regarding each long term MS therapy is provided in the following link (there are links within the links, as well). May they serve as useful resources, to be used in conjunction with your doctor, to anyone considering commencing or changing a Disease Modifying Therapy.


Best of luck,