1ST REBIF

[mercadies25]

Ok, I just want to know is it unusual to have a severe headache, other than that I had no other problem.

I was so scared and it wasn't bad at all. If it stops or slows the progression I can handle it.

I only am on the 8.8 mg. so I know it may get a little tougher.

[TLC_31]

Side effects such as headaches are common for those of us using interferons. In my case (with Avonex) the effects were most severe in the first shots. A regiment of hydration and over-the-counter meds (such as Tylenol, Advil, Aleve) can help mitigate those headaches and other flu-like symptoms.

I am glad you are able to battle this disease, and that shot #1 was relatively uneventful for you.

[Sapphiresgold]

Dehydration can make a mild reaction worse. It is possible you were dehydrated and got a headache from that. Sounds like you might have stressed yourself out a bit about it. That's normal. Hang in there.

I am on Rebif as well. Haven't had any hugely bad side effects. I guess I've been lucky!

[maximumlite]

Headaches have been one constant thing with my MS over the years usually severe. In the beginning of starting my Rebif I got some slight headaches but they went away. I do make sure to hydrate well on shot day and take 2 Ibuprofen a hour before my shot and I also take an Aleve with my shot. I never get a fever till the next day and just take an Aleve in the morning and than am good. Good luck with your shots and hopefully you will have no side effects.

[Krysalus]

Headaches

Hi Mercadies!

When I was taking Rebif, I had a lot of headaches as well. I found that taking either tylenol, advil or motrin before the shot helped minimize the headache. I also started doing the shots at night in effort to sleep through the side effects. I read a lot about it here and found that many people find the side effects get minimized over time as your body gets used to the medication.