A question on SPMS progression

[Grade1]

I am an rrmser (dg five years ago) with active ms and symptoms from several parts of the central nervous system (brainstem, spine, cerebellum; not that much ocular). Thankfully, I don't have permanent disabilities so far. I still have relapses.

To my question. When a person with ms enters the secondary progressive stage, will the progression "hit" those areas of the CNS that have already posed problems in the rrms stage, that is, areas with previous inflammatory lesions?

In other words, if a mser had problems with recurrent optic neuritis, will sight be the area that is going to get worse in the SPMS stage for this individual? And what if there was, despite the problems, no permanent disability at the point of entering the spms stage. Would eyesight still most likely to be "the most likely to go" first.

I hope you get the point Calling for your personal experience!

[twisterred]

There are lots of variables when it comes to MS.

This Summer 2009 magazine by The Rocky Mountain MS Center might help.

http://www.mscenter.org/images/stori...er09lowres.pdf

[Thinkimjob]

I don't really know. This is anecdotal. I was diagnosed with ON, and numb fingers.

I was told if you had sensory symptoms at diagnosis, you generally had a better prognosis than if you had motor problems.

I took dmds from the start.

Over the years, a few more fingers got numb, and I had the occasional tingling numb from the feet up to the chest flare.
It always, except for the fingers, got better.

My first big flare was 3 years ago. I couldn't walk, my balance completely went, and my feet were completely numb.

Presumably those areas had been 'hit', before but quietly, so I didn't notice.
IV 'roids fixed the worst of it, but the damage kept rearing is head whenever I got hot or tired.

In August, I had another big flare, and while things are a little better, the damage is here to stay.

MS is there nibbling away at your myelin, flare or no flare. That's just my opinion, mind.

[Doodlebug]

I was dx in 1994 w/ON. Never completely cleared up. Had ON in the other eye in 1996. Not many sx until I was pregnant in 2001.

While pregnant had this continuous "zaps" that felt like a stun gun that would leave me paralyzed on the l. side for periods of time. Usage of my l. side has gone since then.

I am currently on disability due to l. side paralysis but my MS initially started out with ON.

Hope this helps...