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TO HAWKGIRL-- RE:MS CAUSED BY VIRUS

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    TO HAWKGIRL-- RE:MS CAUSED BY VIRUS

    Hi hawkgirl--

    this study was published on Jan 4th. I though of you when i read it. An investigation of post mortem ms brains that did find a virus in post mortem ms brains, that raises the possibility that some MS is actually caused by a virus and not an autoimmune reaction..but caused by a virus in a way not thought of before.

    History: ms has long been speculated to be a combination of genetic susceptibility & some kind of environmental trigger that starts the auto immune reaction.

    the eb virus has long been suspected as the trigger but has never been proven to be the trigger. the virus that causes mono, most people have been exposed to it, a person can get mono so lightly they don't even know they have gotten EBV, and EBV has a chemical structures similar to myelin.

    Past/Current theory: it was thought that the immune system began fighting EBV, got confused between myelin & EBV then just continued to attack myelin once EBV had been destroyed. Starting an autoimmune disease in people genetically susceptible to MS.

    This Article Theory: This article reports the findings of post mortem brain study of people with MS and the study actually found the EBV in MS brains....indicating an MS person's immune system might not be attacking 'self' but actually attacking a virus, the long suspected EB virus.

    the article theory is a person who ultimately gets ms, gets EBV. the EB virus hides in white blood cells in the persons immune system. then the persons own immune system acts like a trojan horse bringing the virus into the brain/CNS tissue. the virsus then goes dormat in brain/CNS tissue where it sends out RNA messages to surrounding CNS tissue. likely in the process of replicating, spreading, i assume. the immune system then attacks these RNA messages from the dormant virus and that cause the MS episodes thought to be attacking self tissue but its actually attacking a virus RNA messages..

    MS CONTAGIOUS: I still stand by my assertion the MS is not contagious by person to person transmission because the statistics do not show that there is any known person to person transmission. And this is a rather important subject for a person with MS to be certain of or we would end up being treated as lepers. we need to be able to disclose we have a non-contagious muscular/nervous disorder when we want to protect our privacy at work,but continue to be employed. disclose only as much as needed and no more. its a muscular-nervous disorder & its not contagious.

    direct human to human transmissions follow a statistical pattern for each type of transmission & MS has never achieved a statistically significant level of any of the "known" human to human transmission to be any thing more than chance or genetic susceptibility.

    read it your self to see what you think about the study. it gets rather difficult to follow with the theory of hiding in immune system then going dormant in the brain?

    http://www.qmul.ac.uk/media/news/items/smd/61524.html
    xxxxxxxxxxx

    #2
    At a support grp mtg on Monday the nuero was speaking about this, he says he is part of a study (very small grp of researchers) that are looking at this, thier feeling is that everyone is exposed to a virus of some sort very early in life, most bodys are able to fight off the virus and they are never effectad by it, those of us with MS have for some reason not been able to fight it off, and it is what causes the bodies immune system to go into overdrive and causing our problems , they do not feel it is autoimmune but rather something causing the imune system to go crazy trying to kill the virus.
    Plan for the future, but not too hard; it’s not your decision anyway

    Comment


      #3
      One neuro suggested that mine may have been triggered when I was 17. I am 61 now. My sister who was 7 brought home chicken pox from school and I had had a vaccination at school the same day. I got the chicken pox from my sister and somehow it turned into what they called Cox Pow. Instead of little chicken Pox all over my body, I had huge vaccinations all over my body. It took 3 weeks to heal. I live in a very small town in North east Florida and two other kids older than I who went to the same church developed MS early in life. They are both in a wheel chair and can not even feed themselves. Strange!

      Comment


        #4
        EBV

        Most people on this site with MS have had EBV. I had it when I was 18. I read just yesterday, to which I am sure you're referring, that a Zurich doctor has concluded a study. After years of suspision, many docs think they're close to revealing that EBV is either the trigger for MS or is present as a result of the onset of MS. It's about time they finally concluded this!

        Comment


          #5
          Is there a cure or a better way to treat it?

          Comment


            #6
            Originally posted by ffjosh View Post
            Is there a cure or a better way to treat it?
            Sorry no cure yet, just the drugs to modify MS & manage the things it can do to your body.Like bladder problums,spasisity(sp),foot drop,etc.
            Pray for a cure,Nona Judy

            Comment


              #7
              ffjosh,
              I'm not sure what you mean. Please clarify.

              Comment


                #8
                ffjosh - do you mean for EBV ?

                This theory wouldn't surprise me at all because my ITP autoimmune blood disorder was triggered after exposure to someone with a bad virus and pneuomonia. That was over 30 years ago and my doctor at the time indicated it was most likely triggered by the virus exposure.

                Comment


                  #9
                  So am I triumphantly vindicated?

                  I was never trying to say that MS is a virus or that MS is contagious. I was trying to say ... what makes a normal, healthy immune system turn against your body? There are two possibilities to me: either you never had a healthy immune system (suggesting MS is genetic) or there is a trigger, something that happens that for some people, causes our immune systems to go haywire and mess up. I was just trying to say that I think that trigger could be a virus that for many is a harmless virus that they don't even notice, but for us, it triggers a messed up response from our immune systems.

                  Actually that would still mean MS is genetic in some way, because what makes one person's immune system "immune" to such a virus, while another person's immune system goes off the rails?

                  And I still say that until they figure out what causes these autoimmune diseases, they will not find a cure. It's troubling how many of the treatments for MS were discovered by accident, or that have this on the patient information: "It is not known how this medication works."
                  Proud Mom of three kids!
                  dx'd 1996

                  Comment


                    #10
                    Type-1 diabetes, another auto-immune disease has a similar pattern. I was formally Dx'd diabetic after landing in the hospital following a minor sore throat. It seems quite common among T-1 diabetics.

                    I forget the details or where I read about it, but there is a joint research study regarding a common type-1/juvenile diabetes and MS link.

                    Gomer

                    Comment


                      #11
                      Two months before I got optic neuritis I broke out in these big hives all over my torso for three days. I have never had hives before and I still think it was some kind of viral exposure then that triggered my MS. Lyme Disease in my case. I had the Lyme tests and they were both positive but my drs. chose not to treat me and just said my Lyme triggered MS. I definitely believe in the viral-trigger theory (with yes, suseptible genes).

                      Comment


                        #12
                        i, like gomer am t-1 diabetic. mine was juvinile onset (when i was 4). i don`t know the study`s name, but i know they (the "experts") are looking into a possible link. i just wanted to give gomer`s statement some credibility, although none is usually needed when gomer says something.
                        hunterd/HuntOP/Dave
                        volunteer
                        MS World
                        hunterd@msworld.org
                        PPMS DX 2001

                        "ADAPT AND OVERCOME" - MY COUSIN

                        Comment


                          #13
                          Originally posted by Hawkgirl View Post
                          It's troubling how many of the treatments for MS were discovered by accident, or that have this on the patient information: "It is not known how this medication works."
                          Actually, new drugs are routinely tried on many different diseases to test their effectiveness.

                          I'm not sure "by accident" is the right phrase. Scientists are often working in uncharted territory. For example, the brightest minds, working throughout the history of the world, have been unable to successfully unravel the mystery of how we got here, how the Universe began. They have theories, but that's all. Similarly, where the human body is concerned, scientists are being asked to do more than what most of us would consider "smart"...they are seeking knowledge which does not yet exist.


                          rex

                          Comment


                            #14
                            It's troubling how many of the treatments for MS were discovered by accident, or that have this on the patient information: "It is not known how this medication works."
                            The same is with alot of drugs, viagra was a blood pressure medicine and guess what the big side effect of it was with male patients.
                            Plan for the future, but not too hard; it’s not your decision anyway

                            Comment


                              #15
                              Originally posted by Scooter24 View Post
                              The same is with alot of drugs, viagra was a blood pressure medicine and guess what the big side effect of it was with male patients.
                              "Big" side-effect - I get it.

                              My favorite "male enhancement" commercials were the ones for Enzyte, with "Bob", the guy with the "big" smile.


                              rex

                              Comment

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